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The first preparation to fulfill these criteria, currently in 27 nations around the globe, is nabiximols (US Adopted name, also known as Sativex), an oromucosal spray produced from whole cannabis extracts whose effects begin in 15–40 min, allowing a therapeutic window for control of symptoms without intoxication.
In reality, patients are not seeking altered states from their medicine, but rather relief of pain or other complaints.
An additional requirement is a supply chain that ensures security that it is being distributed to its intended target patients. doi: 10.3109/08958370902748559 Pub Med Abstract | Cross Ref Full Text | Google Scholar Pope, H.
The problem is compounded by the facts that technically almost all laboratories pursuing phytocannabinoid analyses in the USA are doing so illegally, most without benefit of a Schedule I license from the Drug Enforcement Administration (DEA). Effect of delta-9-tetrahydrocannabinol and cannabidiol on nocturnal sleep and early-morning behavior in young adults.